The comparative analysis of phosphatidylcholine and phosphatidylserine is of considerable importance within the domains of cell biology and nutritional neuroscience, owing to their pivotal roles in membrane architecture and neurophysiological processes (van Meer et al., 2008; Glade & Smith, 2015). Although both molecules are classified as phospholipids and share a common glycerophospholipid backbone, significant differences in their molecular composition, biophysical properties, and physiological functions warrant careful examination.